The nucleic acid metabolism of animal cells in vitro: I. The incorporation of 14C-formate
作者： R.M.S. Smellie , R.Y. Thomson , J.N. Davidson
DOI: 10.1016/0006-3002(58)90146-X
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摘要: Abstract 1. (1) The incorporation of 14 C-formate into the nucleic acid bases a variety rapidly-growing avian and mammalian tissues has been studied in vivo vitro . 2. (2) In incorporate extensively their purines DNA thymine. most studied, particularly Ehrlich ascites tumour mouse, is depressed although thymine remains high. However, chick embryo liver rat regenerating after partial hepatectomy, pattern same as 3. (3) carcinoma greatly increased by addition 5-amino-4-imidazole carboxamide its riboside or particle-free extract mouse liver. Addition glycinamide ribotide no effect. 4. (4) significance these results discussed.
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Bruce Levenberg, Irving Melnick, John M. Buchanan, Biosynthesis of the purines. XV. The effect of aza-L-serine and 6-diazo-5-oxo-L-norleucine on inosinic acid biosynthesis de novo. Journal of Biological Chemistry. ,vol. 225, pp. 163- 176 ,(1957) , 10.1016/S0021-9258(18)64919-1
Richard A. Peabody, David A. Goldthwait, G. Robert Greenberg, The structure of glycinamide ribotide. Journal of Biological Chemistry. ,vol. 221, pp. 1071- 1081 ,(1956) , 10.1016/S0021-9258(18)65218-4
J. Frank Henderson, G.A. LePage, Purine biosynthesis de novo in mouse tissues and a mouse tumor. Journal of Biological Chemistry. ,vol. 234, pp. 2364- 2368 ,(1959) , 10.1016/S0021-9258(18)69815-1
Martin P. Schulman, John C. Sonne, John M. Buchanan, Biosynthesis of the purines. I. Hypoxanthine formation in pigeon liver homogenates and extracts. Journal of Biological Chemistry. ,vol. 196, pp. 499- 512 ,(1952) , 10.1016/S0021-9258(19)52384-5
Halvor N. Christensen, Thomas R. Riggs, Concentrative uptake of amino acids by the Ehrlich mouse ascites carcinoma cell. Journal of Biological Chemistry. ,vol. 194, pp. 57- 68 ,(1952) , 10.1016/S0021-9258(18)55854-3
G. W. Crosbie, R. M. S. Smellie, J. N. Davidson, Phosphorus compounds in the cell. 5. The composition of the cytoplasmic and nuclear ribonucleic acids of the liver cell Biochemical Journal. ,vol. 54, pp. 287- 292 ,(1953) , 10.1042/BJ0540287
Standish C. Hartman, Bruce Levenberg, John M. Buchanan, BIOSYNTHESIS OF THE PURINES: XI. STRUCTURE, ENZYMATIC SYNTHESIS, AND METABOLISM OF GLYCINAMIDE RIBOTIDE AND (α-N-FORMYL)-GLYCINAMIDE RIBOTIDE Journal of Biological Chemistry. ,vol. 221, pp. 1057- 1070 ,(1956) , 10.1016/S0021-9258(18)65217-2
John M. Buchanan, John C. Sonne, Adelaide M. Delluva, BIOLOGICAL PRECURSORS OF URIC ACID: II. THE RÔLE OF LACTATE, GLYCINE, AND CARBON DIOXIDE AS PRECURSORS OF THE CARBON CHAIN AND NITROGEN ATOM 7 OF URIC ACID Journal of Biological Chemistry. ,vol. 173, pp. 81- 98 ,(1948) , 10.1016/S0021-9258(18)35558-3
Harrington H, Lavik Ps, Nucleic acid metabolism in Ehrlich ascites tumor cells. Cancer Research. ,vol. 17, pp. 43- 47 ,(1957)
R.Y. Thomson, R.M.S. Smellie, J.N. Davidson, The nucleic acid metabolism of animal cells in vitro. II. Characteristics of the in vitro pattern. Biochimica et Biophysica Acta. ,vol. 29, pp. 308- 320 ,(1958) , 10.1016/0006-3002(58)90190-2