Audit of acute Charcot’s disease in the UK: the CDUK study

摘要: Aims/hypothesis We studied factors associated with the development and resolution of acute Charcot foot using a web-based observational study. Methods Clinicians managing cases in UK Ireland between June 2005 February 2007 were invited to register anonymised details on secure website. Results A total 288 (age 57.0±11.3 years [mean±SD]; 71.2% male) registered from 76 centres. Of these, 36% patients recalled an episode relevant trauma preceding 6 months, while 12% had surgery affected foot. In 101 (35%) cases, ulceration was present at registration 20% these osteomyelitis. Non-removable off-loading devices used presentation 35.4% removable 50%. Data available for 219 patients. The median time 9 months whose initial management included use non-removable off-loading, compared 12 remainder (p=0.001). Bisphosphonates administered intravenously 25.4% orally 19.4% cases. who received bisphosphonates longer than those did not (10 p=0.005). Conclusions/interpretation earlier series. Although limited by being non-randomised, data suggest that may shorten resolution. They provide no evidence indicate is beneficial.