Insulin-like growth factor I and II binding in human myometrium and leiomyomas.
作者： Yallampalli Chandrasekhar , James Heiner , Collin Osuamkpe , Manubai Nagamani
DOI: 10.1016/0002-9378(92)91831-T
关键词:
摘要: Objectives: The purpose of this study is to determine if the human myometrium has receptors for insulin-like growth factors I and II whether concentration these increased in leiomyomas. Study Design: Specific binding iodine 125-labeled was examined membrane preparations leiomyomas obtained from 10 women with uterine Results: Binding studies indicate presence specific sites both leiomyoma. factor I, but not II, significantly ( p Conclusion: are compared those myometrium, indicating that may play a role generation and/or tumor.
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