Gitter cells and their relationship to macrophages in the developing cerebellum

摘要: The whole heads of 6 days old rats were exposed to 150R X-ray irradiation. animals sacrificed in a developmental sequence, and the tissue obtained from cerebellum was prepared for electron microscopy. In medullary layer normal resting macrophages could be identified. On basis cytological criteria established control material transformation into reactive studied. They showed an increase cytoplasm, which acquired numerous vacuoles, changes breakdown distribution large clumps heterochromatin nucleus. former gave these cells lattice-like appearance, latter appearance identical that brains neonate microglia adult brains. transformed identified as gitter cells. Issues pertaining relationship between cells, phagocytic are discussed, factors stimulating considered.