Antibiotic prophylaxis during prolonged clean neurosurgery: Results of a randomized double-blind study using oxacillin
作者： Michel Djindjian , Elisabeth Lepresle , Jean-Bernard Homs
DOI: 10.3171/JNS.1990.73.3.0383
关键词:
摘要: The efficacy of oxacillin as a prophylaxis for infection was analyzed in 27-month randomized double-blind study 400 patients who had undergone clean neurosurgical interventions lasting longer than 2 hours. Four neurosurgeons took part the and 356 were eligible final analysis. Among 171 treated with oxacillin, there one case (0.6%), compared to nine (4.9%) 185 given placebo. difference between two groups statistically significant (p = 0.0398). This study, together others (randomized or not), clearly demonstrates antibiotic prolonged neurosurgery.
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