Method and reagents for epithelial barrier formation and treatment of malignant and benign skin disorders by modulating the notch pathway
作者： Brian Nickoloff , Lucio Miele
DOI:
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摘要: In one embodiment, the invention provides a method of inducing differentiation an epithelial cell. another for formation barrier within epithelium. producing differentiated epidermis. assaying genetic propensity patient to develop disorder associated with formation. anther diagnostic test determine expression levels Notch ligands, receptors, or other signaling compounds in cells. novel ligands. preventing retarding progression benign malignant skin.
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