Mechanisms for the formation of membranous nanostructures in cell-to-cell communication

摘要: Cells interact by exchanging material and information. Two methods of cell-to-cell communication are means microvesicles nanotubes. Both nanotubes derive from the cell membrane able to transport contents inner solution. In this review, we describe two physical mechanisms involved in formation nanotubes: curvature-mediated lateral redistribution components with nanodomains; plasmamediated attractive forces between membranes. These clinically relevant since they can be affected drugs. particular, underlying mechanism heparin’s role as an anticoagulant tumor suppressor is suppression microvesicluation due plasma-mediated interaction