Massive somatodendritic sprouting of cortical neurons in Alzheimer's disease

作者: Yasuo Ihara

DOI: 10.1016/0006-8993(88)90293-4

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摘要: In addition to neurofibrillary tangles and senile plaques, antibodies human tau revealed extensive tau-immunoreactive meshworks in layers III V of the neocortex affected with Alzheimer's disease. The consisted innumerable abnormally curly fibers, which were coming from somata dendrites pyramidal cells. Their morphological appearance suggests that those fibers represent somatodendritic sprouting.

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