Highly diastereoselective additions of methoxyallene and acetylenes to chiral α-keto amides
作者： So Won Youn , Yong Hae Kim , Jeong-Wook Hwang , Youngkyu Do
DOI: 10.1039/B100355K
关键词:
摘要: α-Keto amides bearing (S)-indoline chiral auxiliaries reacted with lithiated methoxyallene or lithium acetylides to produce the corresponding dihydrofuranones 7 through formation of tertiary α-hydroxy allenes, tertiary acetylenes, respectively, at −78 °C high diastereoselectivities (up >99% de).
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