Benign Fibro-Osseous Lesions of the Craniofacial Complex A Review

摘要: Benign fibro-osseous lesions of the craniofacial complex are represented by a variety disease processes that characterized pathologic ossifications and calcifications in association with hypercellular fibroblastic marrow element. The current classification includes neoplasms, developmental dysplastic inflammatory/reactive processes. definitive diagnosis can rarely be rendered on basis histopathologic features alone; rather, procurement final is usually dependent upon assessment microscopic, clinical imaging together. Fibrous dysplasia osteitis deformans constitute two which mutations have been uncovered. Other bone diseases include florid osseous dysplasia, focal cemento-osseous periapical cemental all showing predilection for African descent individuals; although no specific genetic alterations DNA coding yet to uncovered most studies derived from predominant high populations. Ossifying fibromas neoplastic four subtypes varying regard behavior propensity recurrence after surgical excision. clinicopathologic molecular this unique heterogeneous group reviewed.