General concept of high-performance amperometric detector for microfluidic (bio)analytical chips.

摘要: In this work, we established theoretically that amperometric detector arrays consisting of a series parallel band microelectrodes placed on the wall microchannel may offer excellent analytical detection performances when implemented onto microfluidic (bio)analytical devices after separative stages. combination with concentration imprinting strategies reported in previous these exceptional be extended to nonelectroactive or poorly diffusing analytes. Using an array electrodes instead large single allows whole core channel probed though keeping time resolution. Thus, analytes close retention times characterized individually resolution which eventually outpaces spectroscopic detections. Such important advantages obtained only through complete understanding complex coupling between diffusional and convective transport molecules solutions near electrochemical detector. As consequence, conditions underlying theoretical data presented work have been selected optimizing procedures rooted analyses. They will fully disclosed further works also establish experimental such detectors validate present concept.