Sbg1 Is a Novel Regulator for the Localization of the β-Glucan Synthase Bgs1 in Fission Yeast
作者： Reshma Davidson , Josef A. Pontasch , Jian-Qiu Wu
DOI: 10.1371/JOURNAL.PONE.0167043
关键词:
摘要: Glucan synthases synthesize glucans, complex polysaccharides that are the major components in fungal cell walls and division septa. Studying regulation of glucan is important as they essential for survival thus popular targets anti-fungal drugs. Linear 1,3-β-glucan main component primary septum synthesized by conserved β-glucan synthase Bgs1 fission yeast cytokinesis. It known Rho1 GTPase regulates catalytic activity F-BAR protein Cdc15 plays a role delivery to plasma membrane. Here we characterize novel Sbg1 present with its levels localization. contractile-ring constriction formation during physically interact interdependent localization less stable and/or mis-targeted vacuoles sbg1 mutants. Moreover, an earlier more trafficking than Cdc15. Together, our data reveal new mode Sbg1.
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