Association of systemic inflammation with the serum apolipoprotein A-1 level: A cross-sectional pilot study
作者： Shigemasa Tani , Ken Nagao , Atsushi Hirayama
DOI: 10.1016/J.JJCC.2015.08.016
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摘要: Abstract Background There is growing evidence to suggest that measurement of apolipoprotein A-1 (apoA-1), the main surface protein on high-density lipoprotein (HDL) particles, superior serum HDL-cholesterol level as a predictor occurrence coronary disease (CAD). We investigated association systemic inflammation an initiator CAD along with apoA-1 level. Methods and results This study was designed hospital-based cross-sectional 652 consecutive outpatients at least one risk factor for investigate relationships between high-sensitivity C-reactive (hs-CRP) peripheral blood white cell (WBC) count April 2009 October 2009. Multivariate analysis after adjustments traditional factors revealed reduced independent indicator higher hs-CRP WBC count, both in overall subject population (β: −0.270 −0.116, p Conclusions Increased levels may be associated decreased counts predictive inflammatory biomarkers onset CAD. In particular, increase decrease useful indices
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