Indium-111 Labeled Cells: New Approaches and Radiation Dosimetry
作者： D. A. Goodwin , C. F. Meares
DOI: 10.1007/978-1-4684-4922-8_17
关键词:
摘要: A large number of mouse monoclonal antibodies (MoAbs) are now available* to human leukocyte cell surface antigens. An incomplete list includes MoAbs specific for T lymphocytes; B associated antigen; a 24,000 dalton structure present on bone marrow lymphohemopoietic precursors and lymphoid leukemic cells; antigens primarily expressed cells lymphocyte monocyte/macrophase lineage; “pan-T” reagent detecting 65,000 antigen (T65) common all normal lymphocytes. This is being increased monthly by several innovative companies* concerned with the development new antibodies. Using bifunctional chelates it possible label In-111 in vivo imaging(1). The advantages disadvantages using listed Table 1.
springer.com
springerlink.com参考文章(50)
Walter Stephen Snyder, "S," absorbed dose per unit cumulated activity for selected radionuclides and organs Society of Nuclear Medicine. ,(1975)
W Chin, J B Hay, T Issekutz, Measurement of lymphocyte traffic with indium-111. Clinical and Experimental Immunology. ,vol. 39, pp. 215- ,(1980)
C. F. Meares, C. I. Diamanti, M. W. Sundberg, D. A. Goodwin, Bifunctional chelates for radio-pharmaceutical labeling. Nuklearmedizin Archive. ,vol. 14, pp. 365- 373 ,(1975) , 10.1055/S-0038-1624918
David M. Goldenberg, Frank H. DeLand, E. Edmund Kim, Guy Simmons, Imaging Approach in Radioimmunodetection Cancer Research. ,vol. 40, pp. 3046- 3049 ,(1980)
David A. Scheinberg, Mette Strand, Leukemic cell targeting and therapy by monoclonal antibody in a mouse model system. Cancer Research. ,vol. 42, pp. 44- 49 ,(1982)
C.I. Diamanti, C.F. Meares, H.D. Fawcett, J.E. Baumert, R.L. Goode, D.J. Sartoris, L.H. DeRiemer, R.L. Lantieri, D.A. Goodwin, Clinical studies with In-111 BLEDTA, a tumor-imaging conjugate of bleomycin with a bifunctional chelating agent. The Journal of Nuclear Medicine. ,vol. 22, pp. 787- 792 ,(1981)
Carol I. Diamanti, Claude F. Meares, Jerrold T. Bushberg, Paul W. Doherty, Martin J. Lipton, David A. Goodwin, Frances K. Conley, Indium-111-labeled autologous platelets for location of vascular thrombi in humans. The Journal of Nuclear Medicine. ,vol. 19, pp. 626- 634 ,(1978)
G Healey, S Osman, H J Danpure, P M Chisholm, Cell damage resulting from the labeling of rat lymphocytes and HeLa S3 cells with In-111 oxine. The Journal of Nuclear Medicine. ,vol. 20, pp. 1308- 1311 ,(1979)
J. Weinstein, R. Parker, A. Keenan, S. Dower, H. Morse, S. Sieber, Monoclonal anitbodies in the lymphatics: toward the diagnosis and therapy of tumor metastases Science. ,vol. 218, pp. 1334- 1337 ,(1982) , 10.1126/SCIENCE.7146917
P. Frost, R. Wiltrout, Z. Maciorowski, N.R. Rose, An isotope release cytotoxicity assay applicable to human tumors: the use of 111indium. Oncology. ,vol. 34, pp. 102- 104 ,(1977) , 10.1159/000225200