Monoclonal anitbodies in the lymphatics: toward the diagnosis and therapy of tumor metastases

作者: J. Weinstein , R. Parker , A. Keenan , S. Dower , H. Morse

DOI: 10.1126/SCIENCE.7146917

关键词:

摘要: Monoclonal antibodies subcutaneously injected into mice track to regional lymph nodes and specifically label target cells there. The lymphatic route of administration can be expected provide much higher sensitivity, target-to-background ratio, faster localization, lower toxicity than the intravenous when aim is diagnose or treat tumor metastases lymphoma in nodes.

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