Infant toenails as a biomarker of in utero arsenic exposure

摘要: A growing body of evidence suggests that in utero and early-life exposure to arsenic may have detrimental effects on children, even at the low moderate levels common United States elsewhere. In a sample 170 mother–infant pairs from New Hampshire, we determined infant by evaluating toenails as biomarker using inductively coupled plasma mass spectrometry. Infant toenail concentration correlated with maternal postpartum concentrations (Spearman’s correlation coefficient 0.34). adjusted linear models, doubling was associated 53.8% increase compared 20.4% for urine concentration. structural equation model, latent variable integrating 67.5% similar between observed validation cohort 130 Rhode Island. occurs through water dietary sources, appear be reliable estimating during critical window gestation.