Regional blood flow distribution in dog during induced hypotension and low cardiac output. Spontaneous breathing versus artificial ventilation.

摘要: Respiratory muscle blood flow and organ was studied in two groups of dogs with radioactively labeled microspheres to assess the influence working respiratory muscles on regional distribution when arterial pressure cardiac output were lowered by pericardial tamponade. In one group (n = 6), paralyzed mechanically ventilated (Mv), while other they left breathe spontaneously (Sb). Cardiac fell 30% control values during tamponade both maintained constant. None hypoxic. Ventilation Sb peaked after 50 min hypotension, but remained unchanged Mv group. Duplicate measurements made a period (corresponding peak ventilation Sb). Blood increased significantly (P less than 0.001) (diaphragmatic 361% values), it decreased Mv. Although comparable groups, different. Sb, received 21% output, compared only 3% Thus, paralysis Mv, large fraction used can be available for perfusion organs low state: flows liver, brain, quadriceps higher Similarly, lactate at all times induction hypotension lower animals 0.005).