Ductal carcinoma in situ of the breast with close or focally involved margins following breast-conserving surgery: treatment with reexcision or radiotherapy with increased dosage.

作者: Amélie Monteau , Brigitte Sigal-Zafrani , Youlia M. Kirova , Virginie Fourchotte , Marc A. Bollet

DOI: 10.1016/J.IJROBP.2008.12.014

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摘要: Purpose Following breast-conserving surgery for DCIS, reexcision before radiotherapy is recommended when margins are close or involved. We investigated whether an additional radiation dose could replace reexcision. Methods selected 208 women with DCIS of the breast treated between 1992 and 2002 who had either ( Results Median follow-up was 89 months. age 53 years 7 patients less than 41. Involved were frequent in non group reexcised (50% vs. 74%, p = 0.0019). All other clinical histological features comparable. whole-breast 50 Gy. total doses to tumour bed 67 Gy (range, 45–77) 60 46–74), respectively Conclusion In carefully

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