Relationship between human papillomavirus (HPV) genotyping and genital neoplasia in HIV-positive patients of Santos City, São Paulo, Brazil.

摘要: Among HIV-positive women, infection with multiple human papillomavirus (HPV) types is known to be more frequent and persistent, as well a greater prevalence of high-grade genital lesions. This study aims characterize, for the first time in Brazil, HPV presence among women high-risk population intraepithelial neoplasia (GIN) development. A non-anonymous, voluntary, cross-sectional epidemiological survey was conducted, from June 1996 April 1997, 141 followed at Center Reference AIDS (CRAIDS). They were submitted gynaecological examination, cytological screening biopsies whenever necessary, GIN DNA detection through polymerase chain reaction (PCR) technique. Positive found 80.8% patients. Two or detected 45% samples. The most 16, 18 (30.5%); 61, 53 (24.4%), non-identified (18.7%). According oncogenic potential, 34.8% considered types. these patients, great variety types, including anogenital environment, young Thus, it should strengthen need periodical careful examination those women.