Human papillomavirus types among women infected with HIV: a meta-analysis.

摘要: HIV-positive women have a high prevalence of human papillomavirus (HPV) infection and are infected with broader range HPV types than HIV-negative women. It is not known to what extent these different associated highgrade squamous intraepithelial lesions (HSIL) cancer. Meta-analysis type-specific among stratified by geographical region cervical cytology: normal atypical cells undetermined significance/low-grade (ASCUS/ LSIL) or HSIL. In 20 studies 5578 were identified largely from North America but also Africa Asia Europe South/Central America. For 3230 no cytological abnormalities was 36.3% for any 11.9% multiple types. The six most common high-risk 16 (4.5%) 58 (3.6%) 18 (3.1%) 52 (2.8%) 31 (2.0%) 33 (2.0%). HPV16 the type in 2053 ASCUS/LSIL 295 Those HSIL significantly less likely be (odds ratio 0.6; 95% confidence interval 0.4-0.7) general female population contrast more 11 51 53 61 proportion rose increasing severity lesions. Nevertheless remained underrepresented who showed higher other compared (authors)