NDUFS4: creation of a mouse model mimicking a Complex I disorder.
作者： Christopher A. Ingraham , Lindsay S. Burwell , Jolanta Skalska , Paul S. Brookes , Robert L. Howell
DOI: 10.1016/J.MITO.2009.02.001
关键词:
摘要: The Complex I NADH dehydrogenase–ubiquinone–FeS 4 (NDUFS4) subunit gene is involved in proper Complex I function such that the loss of NDUFS4 decreases Complex I …
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sci-hub.se 参考文章(24)
Carl A. Pinkert, Robert L. Howell, Catherine L. Donegan, Mouse embryo yield and viability after euthanasia by CO2 inhalation or cervical dislocation. Comparative Medicine. ,vol. 53, pp. 510- 513 ,(2003)
Michael H. Irwin, Wendy K. Pogozelski, Carl A. Pinkert, PCR Optimization for Detection of Transgene Integration Transgenic Animal Technology (Third Edition)#R##N#A Laboratory Handbook. pp. 533- 541 ,(2014) , 10.1016/B978-0-12-410490-7.00019-0
P Soriano, G Friedrich, P Lawinger, Promoter interactions in retrovirus vectors introduced into fibroblasts and embryonic stem cells. Journal of Virology. ,vol. 65, pp. 2314- 2319 ,(1991) , 10.1128/JVI.65.5.2314-2319.1991
Carl A. Pinkert, Transgenic Animal Technology: A Laboratory Handbook ,(2014)
E. Wisniewski, W.S. Kunz, F.N. Gellerich, Phosphate affects the distribution of flux control among the enzymes of oxidative phosphorylation in rat skeletal muscle mitochondria. Journal of Biological Chemistry. ,vol. 268, pp. 9343- 9346 ,(1993) , 10.1016/S0021-9258(18)98356-0
Lambert van den Heuvel, Wim Ruitenbeek, Roel Smeets, Zully Gelman-Kohan, Orly Elpeleg, Jan Loeffen, Frans Trijbels, Edwin Mariman, Diederik de Bruijn, Jan Smeitink, Demonstration of a New Pathogenic Mutation in Human Complex I Deficiency: A 5-bp Duplication in the Nuclear Gene Encoding the 18-kD (AQDQ) Subunit American Journal of Human Genetics. ,vol. 62, pp. 262- 268 ,(1998) , 10.1086/301716
Carl A Pinkert, Ian A Trounce, Production of transmitochondrial mice Methods. ,vol. 26, pp. 348- 357 ,(2002) , 10.1016/S1046-2023(02)00041-5
Shane E. Kruse, William C. Watt, David J. Marcinek, Raj P. Kapur, Kenneth A. Schenkman, Richard D. Palmiter, Mice with Mitochondrial Complex I Deficiency Develop a Fatal Encephalomyopathy Cell Metabolism. ,vol. 7, pp. 312- 320 ,(2008) , 10.1016/J.CMET.2008.02.004
Salvatore Scacco, Vittoria Petruzzella, Sandy Budde, Rosaria Vergari, Rosanna Tamborra, Damiano Panelli, Lambert P. van den Heuvel, Jan A. Smeitink, Sergio Papa, Pathological mutations of the human NDUFS4 gene of the 18-kDa (AQDQ) subunit of complex I affect the expression of the protein and the assembly and function of the complex. Journal of Biological Chemistry. ,vol. 278, pp. 44161- 44167 ,(2003) , 10.1074/JBC.M307615200
S Pitkanen, B H Robinson, Mitochondrial complex I deficiency leads to increased production of superoxide radicals and induction of superoxide dismutase. Journal of Clinical Investigation. ,vol. 98, pp. 345- 351 ,(1996) , 10.1172/JCI118798