Diagnostic accuracy of 18F-FDG-PET/CT in early and late stages of high-risk cutaneous malignant melanoma

摘要: Background The precise role of total body 18F-fluorodeoxyglucose-positron emission tomography/computed tomography (PET/CT) in the clinical management patients with cutaneous malignant melanoma (CMM) is not well established. Objective The purpose this study was to investigate diagnostic accuracy PET/CT early- and late-stage high-risk CMM. Methods We retrospectively analysed various imaging, histopathological data from 97 also examined by during a 5-year period (2007–2011). Three groups were assessed: stage I/II, resected III unresectable III/stage IV. Results The median follow-up time living 43.48 ± 19.67 (15–142) months. We observed high all stages (91.3%, 92.5% 96.2% respectively). appeared be reliable tool even for detection small lymph node metastases. informative 14 19 cases wherein another imaging examination provided inconclusive results regarding lesion dignity. However, less suitable properly evaluating dignity lung lesion. A true positive scan twice as likely clinically negative disease than I/II (35.9% 14.5%, P = 0.007). Conclusions These confirm that an important CMM, but it cannot replace standard care examinations. More accurate clinicopathological timing criteria must defined best utilize advantages method.