Quantitative comparison of the HSV-1 and HSV-2 transcriptomes using DNA microarray analysis
作者： J.S. Aguilar , G.V. Devi-Rao , M.K. Rice , J. Sunabe , P. Ghazal
DOI: 10.1016/J.VIROL.2005.12.036
关键词:
摘要: The genomes of human herpes virus type-1 and type-2 share a high degree sequence identity; yet, they exhibit important differences in pathology their natural host as well animal cell cultures. Here, we report the comparative analysis time relative abundance profiles transcription each type (their transcriptomes) using parallel infections microarray HSV-1 probes which hybridize with efficiency to orthologous HSV-2 transcripts. We have confirmed that transcripts belong same kinetic class; however, temporal pattern accumulation 4 (U(L)4, U(L)29, U(L)30, U(L)31) differs between two types. Interestingly, protein products these are all involved nuclear organization viral DNA localization. discuss relevance findings whether may potential roles pathological HSV-2.
core.ac.uk
ed.ac.uk
osti.gov
elsevier.com
sci-hub.se 参考文章(47)
Edward K Wagner, J.J Garcia Ramirez, S.W Stingley, S.A Aguilar, L Buehler, G.B Devi-Rao, Peter Ghazal, Practical approaches to long oligonucleotide-based DNA microarray: lessons from herpesviruses. Progress in Nucleic Acid Research and Molecular Biology. ,vol. 71, pp. 445- 491 ,(2002) , 10.1016/S0079-6603(02)71048-9
P. Jin, N.R. Ringertz, Cadmium induces transcription of proto-oncogenes c-jun and c-myc in rat L6 myoblasts. Journal of Biological Chemistry. ,vol. 265, pp. 14061- 14064 ,(1990) , 10.1016/S0021-9258(18)77266-9
J D Baines, B Roizman, THE OPEN READING FRAMES UL3, UL4, UL10, AND UL16 ARE DISPENSABLE FOR THE REPLICATION OF HERPES SIMPLEX VIRUS 1 IN CELL CULTURE Journal of Virology. ,vol. 65, pp. 938- 944 ,(1991) , 10.1128/JVI.65.2.938-944.1991
Edward K. Wagner, John F. Guzowski, Jasbir Singh, Transcription of the herpes simplex virus genome during productive and latent infection. Progress in Nucleic Acid Research and Molecular Biology. ,vol. 51, pp. 123- 165 ,(1995) , 10.1016/S0079-6603(08)60878-8
T M Hill, R R Sinden, J R Sadler, Herpes simplex virus types 1 and 2 induce shutoff of host protein synthesis by different mechanisms in Friend erythroleukemia cells Journal of Virology. ,vol. 45, pp. 241- 250 ,(1983) , 10.1128/JVI.45.1.241-250.1983
P R Krause, J M Ostrove, S E Straus, The nucleotide sequence, 5' end, promoter domain, and kinetics of expression of the gene encoding the herpes simplex virus type 2 latency-associated transcript. Journal of Virology. ,vol. 65, pp. 5619- 5623 ,(1991) , 10.1128/JVI.65.10.5619-5623.1991
J F Guzowski, J Singh, E K Wagner, Transcriptional activation of the herpes simplex virus type 1 UL38 promoter conferred by the cis-acting downstream activation sequence is mediated by a cellular transcription factor. Journal of Virology. ,vol. 68, pp. 7774- 7789 ,(1994) , 10.1128/JVI.68.12.7774-7789.1994
T M Hill, J R Sadler, J L Betz, Virion component of herpes simplex virus type 1 KOS interferes with early shutoff of host protein synthesis induced by herpes simplex virus type 2 186. Journal of Virology. ,vol. 56, pp. 312- 316 ,(1985) , 10.1128/JVI.56.1.312-316.1985
H.-Y. Zhu, H. Yamada, Y.-M. Jiang, M. Yamada, Y. Nishiyama, Intracellular localization of the UL31 protein of herpes simplex virus type 2 Archives of Virology. ,vol. 144, pp. 1923- 1935 ,(1999) , 10.1007/S007050050715
Archana Thakur, Sreedharan Athmanathan, Mark Willcox, The differential regulation of nitric oxide by Herpes simplex virus‐1 and ‐2 in a corneal epithelial cell line Clinical and Experimental Ophthalmology. ,vol. 28, pp. 188- 190 ,(2000) , 10.1046/J.1442-9071.2000.00290.X