Circulating MicroRNAs as Biomarkers and Mediators of Cell-Cell Communication in Cancer.
作者： Molly Taylor
DOI: 10.3390/BIOMEDICINES3040270
关键词:
摘要: The realization of personalized medicine for cancer will rely not only on the development new therapies, but biomarkers that direct these therapies to right patient. MicroRNA expression profiles in primary tumor have been shown differ between patients and healthy individuals, suggesting they might make useful biomarkers. However, examination microRNA requires an invasive biopsy procedure. More recently, microRNAs be released from into circulation where can utilized as non-invasive diagnose patients, predict prognosis, or indicate therapeutic response. This review provides overview current use circulating well recent findings their role regulating cell signaling interactions microenvironment.
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Jianning Song, Zhigang Bai, Hua Meng, Yao Yang, Yun Yang, Weirong Li, Jun Zhang, Jie Yin, Xuemei Ma, Tingting Wang, Jin Wang, Wei Han, Zhongtao Zhang, Differential expression of serum miR-126, miR-141 and miR-21 as novel biomarkers for early detection of liver metastasis in colorectal cancer. Chinese Journal of Cancer Research. ,vol. 26, pp. 95- 103 ,(2014) , 10.3978/J.ISSN.1000-9604.2014.02.07
David P Bartel, MicroRNAs: Genomics, Biogenesis, Mechanism, and Function Cell. ,vol. 116, pp. 281- 297 ,(2004) , 10.1016/S0092-8674(04)00045-5
Eun-Jung Jung, Libero Santarpia, Juyeon Kim, Francisco J. Esteva, Erica Moretti, Aman U. Buzdar, Angelo Di Leo, Xiao-Feng Le, Robert C. Bast, Soon-Tae Park, Lajos Pusztai, George A. Calin, Plasma microRNA 210 levels correlate with sensitivity to trastuzumab and tumor presence in breast cancer patients Cancer. ,vol. 118, pp. 2603- 2614 ,(2012) , 10.1002/CNCR.26565
Carl E Freter, Li-Qun Gu, Dali Zheng, Shadi Haddadin, Yong Wang, Michael X Wang, Michael C Perry, Plasma microRNAs as novel biomarkers for early detection of lung cancer. International Journal of Clinical and Experimental Pathology. ,vol. 4, pp. 575- 586 ,(2011)
Jerome Paggetti, Franziska Haderk, Martina Seiffert, Bassam Janji, Ute Distler, Wim Ammerlaan, Yeoun Jin Kim, Julien Adam, Peter Lichter, Eric Solary, Guy Berchem, Etienne Moussay, Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts Blood. ,vol. 126, pp. 1106- 1117 ,(2015) , 10.1182/BLOOD-2014-12-618025
Fulya Yaman Agaoglu, Müge Kovancilar, Yavuz Dizdar, Emin Darendeliler, Stefan Holdenrieder, Nejat Dalay, Ugur Gezer, Investigation of miR-21, miR-141, and miR-221 in blood circulation of patients with prostate cancer Tumor Biology. ,vol. 32, pp. 583- 588 ,(2011) , 10.1007/S13277-011-0154-9
Shine Young Kim, Tae Yong Jeon, Chang In Choi, Dae Hwan Kim, Dong Heon Kim, Gwang Ha Kim, Dong Yup Ryu, Bong Eun Lee, Hyung Hoi Kim, Validation of circulating miRNA biomarkers for predicting lymph node metastasis in gastric cancer. The Journal of Molecular Diagnostics. ,vol. 15, pp. 661- 669 ,(2013) , 10.1016/J.JMOLDX.2013.04.004
Julia Winter, Stephanie Jung, Sarina Keller, Richard I. Gregory, Sven Diederichs, Many roads to maturity: microRNA biogenesis pathways and their regulation. Nature Cell Biology. ,vol. 11, pp. 228- 234 ,(2009) , 10.1038/NCB0309-228
Andrea Ventura, Amanda G. Young, Monte M. Winslow, Laura Lintault, Alex Meissner, Stefan J. Erkeland, Jamie Newman, Roderick T. Bronson, Denise Crowley, James R. Stone, Rudolf Jaenisch, Phillip A. Sharp, Tyler Jacks, Targeted Deletion Reveals Essential and Overlapping Functions of the miR-17∼92 Family of miRNA Clusters Cell. ,vol. 132, pp. 875- 886 ,(2008) , 10.1016/J.CELL.2008.02.019
Hisashi Kanemaru, Satoshi Fukushima, Junji Yamashita, Noritoshi Honda, Rie Oyama, Asako Kakimoto, Shinichi Masuguchi, Tsuyoshi Ishihara, Yuji Inoue, Masatoshi Jinnin, Hironobu Ihn, The circulating microRNA-221 level in patients with malignant melanoma as a new tumor marker Journal of Dermatological Science. ,vol. 61, pp. 187- 193 ,(2011) , 10.1016/J.JDERMSCI.2010.12.010