An examination of adenovirus type 5 mutants for their ability to induce group C adenovirus tumor-specific transplantation antigenicity in rats
作者： Phillip H. Gallimore , Jim Williams
DOI: 10.1016/0042-6822(82)90013-7
关键词:
摘要: Abstract The expression of Group C adenovirus tumor-specific transplantation antigenicity (TSTA) has been examined in rats using a variety type 5 (Ad-5) mutants. Transformation-defective I ElA mutants (other than Ad-5 hrl and hr2 ), II ElB mutants, N gene produced significantly lower TSTA or no when compared with levels induced by Ad-2 wild-type viruses. Two sub 304 ts 125, neither which possess lesions within the transforming sequences, high vivo .
elsevier.com
sci-hub.se 参考文章(38)
S.J. Flint, Joe Sambrook, J.F. Williams, Phillip A. Sharp, Viral nucleic acid sequences in transformed cells: IV. A study of the sequences of adenovirus 5 DNA and RNA in four lines of Adenovirus 5-transformed rodent cells using specific fragments of the viral genome Virology. ,vol. 72, pp. 456- 470 ,(1976) , 10.1016/0042-6822(76)90174-4
Phillip A Sharp, Ulf Pettersson, Joe Sambrook, Viral DNA in transformed cells: I. A study of the sequences of adenovirus 2 DNA in a line of transformed rat cells using specific fragments of the viral genome☆ Journal of Molecular Biology. ,vol. 89, pp. 709- 726 ,(1974) , 10.1016/0022-2836(74)90162-4
Marcia J. Ensinger, Harold S. Ginsberg, Selection and Preliminary Characterization of Temperature-Sensitive Mutants of Type 5 Adenovirus Journal of Virology. ,vol. 10, pp. 328- 339 ,(1972) , 10.1128/JVI.10.3.328-339.1972
Alan S. Rabson, Andrew M. Lewis, James L. Cook, Charles H. Kirkpatrick, Rejection of adenovirus 2-transformed cell tumors and immune responsiveness in Syrian hamsters. Cancer Research. ,vol. 39, pp. 4949- 4955 ,(1979)
R. M. McAllister, M. O. Nicolson, A. M. Lewis, I. Macpherson, R. J. Huebner, Transformation of Rat Embryo Cells by Adenovirus Type 1 Journal of General Virology. ,vol. 4, pp. 29- 36 ,(1969) , 10.1099/0022-1317-4-1-29
David John Finney, Statistical method in biological assay. Statistical method in biological assay.. ,(1952)
Eric Frost, Jim Williams, Mapping temperature-sensitive and host-range mutations of adenovirus type 5 by marker rescue Virology. ,vol. 91, pp. 39- 50 ,(1978) , 10.1016/0042-6822(78)90353-7
K. Shiroki, H. Shimojo, Y. Maeta, C. Hamada, Tumor-specific transplantation and surface antigen in cells transformed by the adenovirus 12 DNA fragments Virology. ,vol. 99, pp. 188- 191 ,(1979) , 10.1016/0042-6822(79)90053-9
P. H. Gallimore, Tumour Production in Immunosuppressed Rats with Cells Transformed in vitro by Adenovirus Type 2 Journal of General Virology. ,vol. 16, pp. 99- 102 ,(1972) , 10.1099/0022-1317-16-1-99
J. Williams, R. S. Galos, M. H. Binger, S. J. Flint, Location of Additional Early Regions within the Left Quarter of the Adenoviral Genome Cold Spring Harbor Symposia on Quantitative Biology. ,vol. 44, pp. 353- 365 ,(1980) , 10.1101/SQB.1980.044.01.040