The association between low level of high-density lipoprotein cholesterol and mood disorder using time-dependent analysis.

摘要: Abstract Background Although many studies have identified factors associated with mood disorder, the association between high-density lipoprotein cholesterol (HDL-C) and disorder is still controversial. The aim of our study was to evaluate low HDL-C onset in Korea based on different cut-off levels. Methods We used National Health Examinations Service cohort data from 2009 2013. time-dependent Cox regression analysis level disorder. Hazard ratios (HRs) for were estimated 1- 2-year time intervals, starting at first health examination accounting duration until next examination. Results A total 400,803 participants (male: 220,573; female: 180,230) included study. 4576 (2.07%) males 7598 (4.22%) females developed Based dyslipidemia ( Conclusions Our findings suggest that potential risk However, a flexible threshold value would be needed subsequent Thus, further are help improve mental susceptible individuals.