Natural products derived from plants as potential drugs for the photodynamic destruction of tumor cells.
作者： R. Ebermann , G. Alth , M. Kreitner , A. Kubin
DOI: 10.1016/S1011-1344(96)07353-8
关键词:
摘要: Abstract Chlorophyll and some of its synthetically produced derivatives are important sensitizers in photodynamic cancer therapy. Other natural products from plants with light dependent activity include quinones like hypericin fagopyrin. These compounds have extended π-electron systems which upon photoexcitation visible responsible for singlet oxygen production. plant constituents show UV induced photosensitizing furanocumarins psoralen angelicin, aflatoxins alkaloids as well thiophene derivatives, therthienyl serveral polyacetylenes. The properties a chelidonium alkaloid derivative data potential clinical applicability given.
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