Anticariogenic and Antibacterial Properties of a Copper Varnish Using an In Vitro Microbial Caries Model

作者: A. Thneibat , M. Fontana , M. A. Cochran , C. Gonzalez-Cabezas , B. K. Moore

DOI: 10.2341/07-50

关键词:

摘要: The antimicrobial and anticariogenic properties of a copper varnish (experimental mixture Doc's Best Red Copper cement Copalite varnish, Cooley Cooley, Ltd, Houston, TX, USA: designated in this study as "Copper Seal") on the root surface were evaluated an vitro microbial caries model. Fifty-six human specimens prepared from anterior teeth randomly divided into four groups: Groups 1 3-Copper Seal; Group 2-chlorhexidine positive control (Cervitec, Ivolcar Vivadent, Schaan, Liechtenstein) 4-a negative that received no treatment. varnishes painted 1, 2 3, then visually removed after 24 hours 1. demineralized model for five days. Plaque was collected to obtain bacterial colonization numbers, sectioned analyzed lesion extent using Confocal Laser Scanning microscopy. There significant differences (p>0.05) among groups terms count. Regarding development, group with (Group 1) non-treated 4) had significantly greater total area lesions fluorescence than without removal 3) chlorhexidine 2). Therefore, it concluded have effects surfaces, tested

参考文章(27)
Evans Dj, Foley J, Lloyd Ch, Blackwell A, Black copper phosphate cement: does it have a future? The European journal of prosthodontics and restorative dentistry. ,vol. 9, pp. 67- 71 ,(2001)
Ch. Splieth, Ch. Schwahn, O. Bernhardt, U. John, Prevalence and distribution of root caries in Pomerania, North-East Germany. Caries Research. ,vol. 38, pp. 333- 340 ,(2004) , 10.1159/000078179
K. J. Bundy, M. F. Butler, R. F. Hochman, An investigation of the bacteriostatic properties of pure metals Journal of Biomedical Materials Research. ,vol. 14, pp. 653- 663 ,(1980) , 10.1002/JBM.820140511
P.L. Rosalen, W.H. Bowen, S.K. Pearson, Effect of copper co-crystallized with sugar on caries development in desalivated rats. Caries Research. ,vol. 30, pp. 367- 372 ,(1996) , 10.1159/000262344
Rita Sorvari, Satu Spets-Happonen, Heikki Luoma, Efficacy of chlorhexidine solution with fluoride varnishing in preventing enamel softening by Streptococcus mutans in an artificial mouth. European Journal of Oral Sciences. ,vol. 102, pp. 206- 209 ,(1994) , 10.1111/J.1600-0722.1994.TB01181.X
S. Balzar Ekenbäck, L.E. Linder, H. Lönnies, Effect of four dental varnishes on the colonization of cariogenic bacteria on exposed sound root surfaces. Caries Research. ,vol. 34, pp. 70- 74 ,(2000) , 10.1159/000016572
M. Fontana, A.J. Dunipace, R.L. Gregory, T.W. Noblitt, Y. Li, K.K. Park, G.K. Stookey, An in vitro Microbial Model for Studying Secondary Caries Formation Caries Research. ,vol. 30, pp. 112- 118 ,(1996) , 10.1159/000262146
J. Afseth, S.M. Amsbaugh, E. Monell-Torrens, W.H. Bowen, G. Rølla, J. Brunelle, E. Dahl, Effect of copper applied topically or in drinking water on experimental caries in rats. Caries Research. ,vol. 18, pp. 434- 439 ,(1984) , 10.1159/000260799
D.B. Miracle, Overview No. 104 The physical and mechanical properties of NiAl Acta Metallurgica Et Materialia. ,vol. 41, pp. 649- 684 ,(1993) , 10.1016/0956-7151(93)90001-9