High Expression of Delta-Like Ligand 4 Predicts Poor Prognosis After Curative Resection for Pancreatic Cancer
作者： Hai-Tao Chen , Quan-Cai Cai , Jian-Ming Zheng , Xiao-Hua Man , Hui Jiang
DOI: 10.1245/S10434-011-1968-9
关键词:
摘要: Background Delta-like ligand 4 (DLL4)-Notch signaling plays a key role in tumor angiogenesis, but its prognostic value patients with pancreatic ductal adenocarcinoma (PDAC) remains unclear. Our aim was to determine whether high DLL4 expression is correlated poor prognosis after curative resection for PDAC.
springer.com
sci-hub.se 参考文章(35)
TNM classification of malignant tumours Published in <b>2010</b> in Chichester, West Sussex, UK ;Hoboken, NJ by Wiley-Blackwell. ,(1987) , 10.1007/978-3-642-82982-6
Yousuke Seo, Hideo Baba, Toshiro Fukuda, Masaki Takashima, Keizo Sugimachi, None, High expression of vascular endothelial growth factor is associated with liver metastasis and a poor prognosis for patients with ductal pancreatic adenocarcinoma Cancer. ,vol. 88, pp. 2239- 2245 ,(2000) , 10.1002/(SICI)1097-0142(20000515)88:10<2239::AID-CNCR6>3.0.CO;2-V
S. Suchting, C. Freitas, F. le Noble, R. Benedito, C. Breant, A. Duarte, A. Eichmann, The Notch ligand Delta-like 4 negatively regulates endothelial tip cell formation and vessel branching Proceedings of the National Academy of Sciences of the United States of America. ,vol. 104, pp. 3225- 3230 ,(2007) , 10.1073/PNAS.0611177104
Stanley Lemeshow, David W. Hosmer, Applied Logistic Regression ,(1989)
Irene Noguera-Troise, Christopher Daly, Nicholas J. Papadopoulos, Sandra Coetzee, Pat Boland, Nicholas W. Gale, Hsin Chieh Lin, George D. Yancopoulos, Gavin Thurston, Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis Nature. ,vol. 444, pp. 1032- 1037 ,(2006) , 10.1038/NATURE05355
Rakesh K Jain, Dan G Duda, Jeffrey W Clark, Jay S Loeffler, Lessons from phase III clinical trials on anti-VEGF therapy for cancer Nature Reviews Clinical Oncology. ,vol. 3, pp. 24- 40 ,(2006) , 10.1038/NCPONC0403
Peter Büchler, Howard A. Reber, Markus W. Büchler, Helmut Friess, Oscar J. Hines, VEGF-RII Influences the Prognosis of Pancreatic Cancer Annals of Surgery. ,vol. 236, pp. 738- 749 ,(2002) , 10.1097/00000658-200212000-00006
Tae-Jung Kim, Youn Soo Lee, Jin-Hyung Kang, Yeon-Sil Kim, Chang Suk Kang, Prognostic significance of expression of VEGF and Cox-2 in nasopharyngeal carcinoma and its association with expression of C-erbB2 and EGFR. Journal of Surgical Oncology. ,vol. 103, pp. 46- 52 ,(2011) , 10.1002/JSO.21767
Hidekazu Oishi, Makoto Sunamura, Shinichi Egawa, Fuyuhiko Motoi, Michiaki Unno, Toru Furukawa, Nagy A. Habib, Hideo Yagita, Blockade of Delta-Like Ligand 4 Signaling Inhibits Both Growth and Angiogenesis of Pancreatic Cancer Pancreas. ,vol. 39, pp. 897- 903 ,(2010) , 10.1097/MPA.0B013E3181CE7185
Adrian M. Jubb, Elizabeth J. Soilleux, Helen Turley, Graham Steers, Andrew Parker, Irene Low, Jennifer Blades, Ji-Liang Li, Paul Allen, Russell Leek, Irene Noguera-Troise, Kevin C. Gatter, Gavin Thurston, Adrian L. Harris, Expression of Vascular Notch Ligand Delta-Like 4 and Inflammatory Markers in Breast Cancer American Journal of Pathology. ,vol. 176, pp. 2019- 2028 ,(2010) , 10.2353/AJPATH.2010.090908