Transrepression of the N-myc expression by c-myc protein.
作者： Yoshihisa Kubota , Sun Hee Kim , Sanae M.M. Iguchi-Ariga , Hiroyoshi Ariga
DOI: 10.1016/0006-291X(89)90771-7
关键词:
摘要: In the human neuroblastoma cell line IMR32 N-myc gene happens to be amplified and actively expressed, whereas no stable c-myc RNA can detected in same cells. this report, we show that cells expression of is repressed by introduction a vector (c-myc cDNA conjugated with an SR promoter). Moreover, dose response experiments showed amount endogenous protein present HeLa (which express but not N-myc) enough repress
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sci-hub.se 参考文章(13)
R. Versteeg, I. A. Noordermeer, M. Krüse-Wolters, D. J. Ruiter, P. I. Schrier, c-myc down-regulates class I HLA expression in human melanomas. The EMBO Journal. ,vol. 7, pp. 1023- 1029 ,(1988) , 10.1002/J.1460-2075.1988.TB02909.X
S. M. Iguchi-Ariga, T. Itani, Y. Kiji, H. Ariga, Possible function of the c-myc product: promotion of cellular DNA replication. The EMBO Journal. ,vol. 6, pp. 2365- 2371 ,(1987) , 10.1002/J.1460-2075.1987.TB02513.X
Suzanne Cory, Activation of cellular oncogenes in hemopoietic cells by chromosome translocation. Advances in Cancer Research. ,vol. 47, pp. 189- 234 ,(1986) , 10.1016/S0065-230X(08)60200-6
Y Takebe, M Seiki, J Fujisawa, P Hoy, K Yokota, K Arai, M Yoshida, N Arai, SR alpha promoter: an efficient and versatile mammalian cDNA expression system composed of the simian virus 40 early promoter and the R-U5 segment of human T-cell leukemia virus type 1 long terminal repeat. Molecular and Cellular Biology. ,vol. 8, pp. 466- 472 ,(1988) , 10.1128/MCB.8.1.466
M Shibuya, J Yokota, Y Ueyama, Amplification and expression of a cellular oncogene (c-myc) in human gastric adenocarcinoma cells. Molecular and Cellular Biology. ,vol. 5, pp. 414- 418 ,(1985) , 10.1128/MCB.5.2.414
F.L. Graham, A.J. van der Eb, A new technique for the assay of infectivity of human adenovirus 5 DNA Virology. ,vol. 52, pp. 456- 467 ,(1973) , 10.1016/0042-6822(73)90341-3
R Kaddurah-Daouk, J M Greene, A S Baldwin, R E Kingston, Activation and repression of mammalian gene expression by the c-myc protein. Genes & Development. ,vol. 1, pp. 347- 357 ,(1987) , 10.1101/GAD.1.4.347
Kari Alitalo, Päivi Koskinen, Tomi P. Mäkelä, Kalle Saksela, Lea Sistonen, Robert Winqvist, myc oncogenes: activation and amplification Biochimica et Biophysica Acta. ,vol. 907, pp. 1- 32 ,(1987) , 10.1016/0304-419X(87)90016-3
Vladimir Glisin, Radomir Crkvenjakov, Craig Byus, Ribonucleic acid isolated by cesium chloride centrifugation. Biochemistry. ,vol. 13, pp. 2633- 2637 ,(1974) , 10.1021/BI00709A025
Robert E. Kingston, Albert S. Baldwin, Phillip A. Sharp, Regulation of heat shock protein 70 gene expression by c-myc. Nature. ,vol. 312, pp. 280- 282 ,(1984) , 10.1038/312280A0