Risk factors and prognosis for corneal ectasia after LASIK

摘要: Abstract Purpose To review cases of corneal ectasia after laser in situ keratomileusis (LASIK), identify preoperative risk factors, and evaluate methods success rates visual rehabilitation for these cases. Design Retrospective nonrandomized comparative trial. Participants Ten eyes from seven patients identified as developing LASIK, 33 previously reported cases, two control groups with uneventful LASIK normal postoperative courses: 100 consecutive (first group), high myopia (> 8 diopters [D]) preoperatively (second group). Methods data each case compared that courses. Main outcome measures Preoperative refraction, topographic features, residual stromal bed thickness (RSB), time to the development ectasia, number enhancements, final best-corrected acuity (BCVA), method correction. Results Length follow-up averaged 23.4 months (range, 6–48 months) LASIK. Mean 16.3 1–45 months). refraction −8.69 D −5.37 first group ( P = 0.005). Preoperatively, 88% met criteria forme fruste keratoconus, 2% 0.0000001). Seven (70%) had RSB 0.0004) second (256.5 μm; 0.04). enhancements. Only 10% lost more than one line BCVA, all eventually achieved corrected vision 20/30 or better. One required penetrating keratoplasty (10%), while others rigid gas-permeable contact lenses Conclusions Significant factors include myopia, low RSB. All at least factor other significant differences remained even when controlling myopia. Multiple enhancements were common among affected but their causative role remains unknown. We did not any who developed without recognizable factors.