TRIM21 Ubiquitylates SQSTM1/p62 and Suppresses Protein Sequestration to Regulate Redox Homeostasis

作者: Ji-An Pan , Yu Sun , Ya-Ping Jiang , Alex J. Bott , Nadia Jaber

DOI: 10.1016/J.MOLCEL.2016.02.007

关键词:

摘要: … TRIM21 is a RING finger domain-containing ubiquitin E3 ligase whose expression is elevated in autoimmune disease. While TRIM21 … Here we show that TRIM21 plays an essential role …

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