Prevalence of intrahepatic cholestasis of pregnancy in La Paz, Bolivia.

作者: Humberto Reyes , Gonzalo Taboada , Jose Ribalta

DOI: 10.1016/0021-9681(79)90111-5

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摘要: Abstract A past history of intrahepatic cholestasis pregnancy—either as cholestatic jaundice or pruritus gravidarum—was inquired in 304 pregnant women examined La Paz, Bolivia. Pruritus gravidarum was detected 9.2% them but no cases pregnancy were found the sample studied. This prevalence rate is considerably greater than that reported European and North American populations (0.2–3.0%) smaller Araucanian Indian-mixed (22.1%) Caucasoids (12.6%) previously studied Chile. No significant differences rates between four ethnic groups (Aimara Indian. Quechua Indian, Caucasoids) which Bolivian classified. Chilean showing a degree admixture with South Indian their ancestry, had recurrence Caucasoid native groups. We propose Bolivia Chile influenced by genetic predisposition related to some Still unidentified environmental factors may modify expressivity disease.

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