摘要: In PNAS, Kapoor et al. (1) discover a Flaviviridae agent most closely related to hepatitis C virus (HCV); the identified RNA genome was isolated from domestic dogs with respiratory illness. This might shed new light on origin and evolution of HCV could lead surrogate model systems for this important human pathogen. Over 100 million people are affected by worldwide, but research has been hampered lack widely available animal models representative culture systems. Thus, discovery an homolog in gives hope finding ways study deadly virus.