Emergence and Spread of SARS-CoV-2 Lineages B.1.1.7 and P.1 in Italy.
作者： Francesca Di Giallonardo , Joanna C A Cobbin , Iolanda Mangone , Edward C Holmes , Cesare Cammà
DOI: 10.3390/V13050794
关键词:
摘要: Italy's second wave of SARS-CoV-2 has hit hard, with more than three million cases and over 100,000 deaths, representing an almost ten-fold increase in the numbers reported by August 2020. Herein, we present analysis 6515 sequences sampled Italy between 29 January 2020 1 March 2021 show how different lineages emerged multiple times independently despite lockdown restrictions. Virus lineage B.1.177 became dominant variant November 2020, when peaked at 40,000 a day, but since this is being replaced B.1.1.7 'variant concern'. In addition, report sudden another documented concern-lineage P.1-from December onwards, most likely caused single introduction into Italy. We again highlight international importations drive emergence new that genome sequencing should remain top priority for ongoing surveillance
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