Bridging Immunotoxicology to Clinical Drug Development

Robert W Luebke, Christine Parks, Michael I Luster, None, Suppression of immune function and susceptibility to infections in humans: association of immune function with clinical disease. Journal of Immunotoxicology. ,vol. 1, pp. 15- 24 ,(2004) , 10.1080/15476910490438342

V. Hamarström, K. Pauksen, H. Svensson, G. Öberg, C. Paul, P. Ljungman, Tetanus immunity in patients with hematological malignancies Supportive Care in Cancer. ,vol. 6, pp. 469- 472 ,(1998) , 10.1007/S005200050196

G. Choquet-Kastylevsky, J. Descotes, Value of animal models for predicting hypersensitivity reactions to medicinal products Toxicology. ,vol. 129, pp. 27- 35 ,(1998) , 10.1016/S0300-483X(98)00060-2

Shukal Bala, James Weaver, Kenneth L. Hastings, Clinical relevance of preclinical testing for allergic side effects Toxicology. ,vol. 209, pp. 195- 200 ,(2005) , 10.1016/J.TOX.2004.12.030

Jack H Dean, Michael I Luster, Gary A Boorman, Robert W Leubke, Lloyd D Lauer, None, Application of tumor, bacterial and parasite susceptibility assays to study immune alterations induced by environmental chemicals Environmental Health Perspectives. ,vol. 43, pp. 81- 88 ,(1982) , 10.1289/EHP.824381

Christine McCusker, Wendy Somerville, Vijaylaxmi Grey, Bruce Mazer, Specific Antibody Responses to Diphtheria/Tetanus Revaccination in Children Evaluated for Immunodeficiency Annals of Allergy Asthma & Immunology. ,vol. 79, pp. 145- 150 ,(1997) , 10.1016/S1081-1206(10)63101-8

Joseph Keane, Sharon Gershon, Robert P. Wise, Elizabeth Mirabile-Levens, John Kasznica, William D. Schwieterman, Jeffrey N. Siegel, M. Miles Braun, Tuberculosis associated with infliximab, a tumor necrosis factor alpha-neutralizing agent The New England Journal of Medicine. ,vol. 345, pp. 1098- 1104 ,(2001) , 10.1056/NEJMOA011110

H HILL, T MARTINS, The flow cytometric analysis of cytokines using multi-analyte fluorescence microarray technology. Methods. ,vol. 38, pp. 312- 316 ,(2006) , 10.1016/J.YMETH.2005.11.014

CJ Burns, PJ Burns, MP Holsapple, 'of Mice and men' (John steinbeck)-How do we determine the potential for immunotoxicity in humans? Annals of Epidemiology. ,vol. 10, pp. 471- 472 ,(2000) , 10.1016/S1047-2797(00)00100-9

Richard M. Ransohoff, “Thinking without thinking” about natalizumab and PML Journal of the Neurological Sciences. ,vol. 259, pp. 50- 52 ,(2007) , 10.1016/J.JNS.2006.04.011