TNF-Receptor Inhibitor Therapy for the Treatment of Children with Idiopathic Pneumonia Syndrome. A Joint Pediatric Blood and Marrow Transplant Consortium and Children's Oncology Group Study (ASCT0521)
作者： Gregory A. Yanik , Stephan A. Grupp , Michael A. Pulsipher , John E. Levine , Kirk R. Schultz
DOI: 10.1016/J.BBMT.2014.09.019
关键词:
摘要: Abstract Idiopathic pneumonia syndrome (IPS) is an acute, noninfectious lung disorder associated with high morbidity and mortality after hematopoietic cell transplantation. Previous studies have suggested a role for TNFα in the pathogenesis of IPS. We report multicenter phase II trial investigating soluble TNF-binding protein, etanercept (Enbrel, Amgen, Thousand Oaks, CA), treatment pediatric patients Eligible were
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