摘要: Accumulating evidence over the last decade has presented us with intriguing observation that majority of eukaryotic genomes are pervasively transcribed to encode a complex network small and long noncoding RNAs. Long RNAs particular interest, as they were once thought be restricted housekeeping functions now linked wide variety biological related physiology, embryology development. Emerging indicates subset mediate their by using chromatin substrate, index genetic information encoded in genome. This chapter will discuss how processes underlying transcription transcriptional regulation, epigenetically regulating structure various contexts.
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