Photodynamic Activity of Fullerene Derivatives Solubilized in Water by Natural-Product-Based Solubilizing Agents.
作者： Daiki Antoku , Kouta Sugikawa , Atsushi Ikeda
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摘要: Water-soluble fullerenes prepared by using solubilizing agents based on natural products are promising photosensitizers for photodynamic therapy. Cyclodextrin, β-1,3-glucan, lysozyme, and liposomes can stably solubilize not only C60 C70 , but also some derivatives in water. To improve the solubilities of fullerenes, specific methods have been developed each agent. exhibit photoinduced cytotoxicity under near-ultraviolet irradiation, at wavelengths over 600 nm, which appropriate However, dyad complexes solubilized combined with light-harvesting antenna molecules cytotoxicities nm. Furthermore, controlling fullerene molecule positions within affects performance photosensitizer.
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