RNF115 promotes lung adenocarcinoma through Wnt/β-catenin pathway activation by mediating APC ubiquitination.
作者： Qing Cui , Ming Zhang , Xiao-Yue Cai , Yun Dong , Xiao-Ting Wu
DOI: 10.1186/S40170-021-00243-Y
关键词:
摘要: Patients with lung adenocarcinoma (LUAD) have high mortality rate and poor prognosis. The LUAD cells display increased aerobic glycolysis, which generates energy required for their …
biomedcentral.com
springer.com 
sci-hub.st 参考文章(43)
Wanming Hu, Huadong Chen, Shaoyan Xi, Jiabin Lu, Xinke Zhang, Qiuliang Wu, Zhihai Zhong, Jing Zeng, Downregulation of ring-finger protein 43 in glioma associates with poor prognosis. International Journal of Clinical and Experimental Pathology. ,vol. 8, pp. 490- 496 ,(2015)
Zehua Wang, Zhi Nie, Wenlin Chen, Zhongmei Zhou, Qinghua Kong, Arun K. Seth, Rong Liu, Ceshi Chen, RNF115/BCA2 E3 Ubiquitin Ligase Promotes Breast Cancer Cell Proliferation through Targeting p21Waf1/Cip1 for Ubiquitin-Mediated Degradation Neoplasia. ,vol. 15, pp. 1028- 1035 ,(2013) , 10.1593/NEO.13678
Siddhartha Devarakonda, Daniel Morgensztern, Ramaswamy Govindan, Genomic alterations in lung adenocarcinoma The Lancet Oncology. ,vol. 16, pp. e342- e351 ,(2015) , 10.1016/S1470-2045(15)00077-7
Piri L Welcsh, Kelly N Owens, Mary-Claire King, Insights into the functions of BRCA1 and BRCA2. Trends in Genetics. ,vol. 16, pp. 69- 74 ,(2000) , 10.1016/S0168-9525(99)01930-7
Yi Sun, E3 ubiquitin ligases as cancer targets and biomarkers. Neoplasia. ,vol. 8, pp. 645- 654 ,(2006) , 10.1593/NEO.06376
Beibei Wu, Sarah Piloto, Weihua Zeng, Nate P Hoverter, Thomas F Schilling, Marian L Waterman, Ring Finger Protein 14 is a new regulator of TCF/β-catenin-mediated transcription and colon cancer cell survival. EMBO Reports. ,vol. 14, pp. 347- 355 ,(2013) , 10.1038/EMBOR.2013.19
K. L. Lorick, J. P. Jensen, S. Fang, A. M. Ong, S. Hatakeyama, A. M. Weissman, RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination Proceedings of the National Academy of Sciences of the United States of America. ,vol. 96, pp. 11364- 11369 ,(1999) , 10.1073/PNAS.96.20.11364
Angelika Burger, Yutaka Amemiya, Richard Kitching, Arun K. Seth, Novel RING E3 Ubiquitin Ligases in Breast Cancer Neoplasia. ,vol. 8, pp. 689- 695 ,(2006) , 10.1593/NEO.06469
Hans Clevers, Roel Nusse, Wnt/β-catenin signaling and disease. Cell. ,vol. 149, pp. 1192- 1205 ,(2012) , 10.1016/J.CELL.2012.05.012
Fathima R. Kona, Karri Stark, Luke Bisoski, Daniela Buac, Qiuzhi Cui, Q. Ping Dou, Transcriptional activation of breast cancer-associated gene 2 by estrogen receptor. Breast Cancer Research and Treatment. ,vol. 135, pp. 495- 503 ,(2012) , 10.1007/S10549-012-2107-4