Expression monitoring by hybridization to high density nucleic acid arrays

摘要: This invention provides methods of monitoring the expression levels a multiplicity genes. The involve hybridizing nucleic acid sample to high density array oligonucleotide probes where contains complementary subsequences target acids in sample. In one embodiment, method involves providing pool comprising RNA transcripts or more genes, derived from transcripts, said an immobilized on surface, than 100 different oligonucleotides and each is localized predetermined region greater about 60 per 1 cm 2 , olignucleotide are transcripts; quantifying hybridized array.