Neural Drive and Electromechanical Alterations in the Fatiguing Diaphragm

摘要: It is suggested that respiratory failure in the compromised circulation might occur as a result of muscle fatigue presence adequate neural drive and excitation. As cardiac output decreases acidosis develops ventilation increases, resulting an increase work breathing, which requires delivery large supplies energy. these demands cannot be met by energy supply, because low output, diaphragm fails force generator ensues. Diaphragmatic may normal subjects if pressure developed with each breath greater than 40% maximum transdiaphragmatic hypoxia predisposes to fatigue. fatigue, other skeletal muscles, located either at neuromuscular junction or distal it can detected phrenic stimulation frequency analysis myoelectric signal. Phrenic shows after less any stimulation, but loss frequencies persists for longer period high frequencies. Frequency electromyogram reveals power spectrum shifts lower This shift occurs long before generator.