Voltage-dependent calcium currents in Purkinje cells from rat cerebellar vermis.
作者： LJ Regan
DOI: 10.1523/JNEUROSCI.11-07-02259.1991
关键词:
摘要: Whole-cell patch clamp recording was used to characterize calcium currents in Purkinje cells dissociated from the cerebellar vermis of 1- 3-week postnatal rats. A subset had a low-threshold, transient current similar T-type peripheral neurons. All high-threshold, slowly inactivating current. Only small component high-threshold sensitive dihydropyridine (DHP) antagonists or agonist BAY K8644. omega-Conotoxin very little effect on The results suggest that these have at least three types channels: channels (present only fraction cells), DHP-sensitive L-type (contributing current), and predominant type high- threshold channel is pharmacologically distinct N- characterized
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