Lactoferrin and free secretory component of human milk inhibit the adhesion of enteropathogenic Escherichia coli to HeLa cells.

摘要: Background Diarrhoea caused by Escherichia coli is an important cause of infant morbidity and mortality in developing countries. Enteropathogenic (EPEC) considered one the major causes diarrhoea children living The ability diarrhoeagenic strains E. to adhere colonize intestine first step towards disease. EPEC enterocytes HeLa cells a characteristic pattern known as localized adherence. Many epidemiological studies have shown that breast-feeding protects infants from intestinal infections. Both immunoglobulin non-immunoglobulin elements human milk are thought contribute protection diarrhoeal agents.