Intestinal calcium absorption as shown by stable strontium test in celiac disease before and after gluten-free diet.

摘要: Objectives : To investigate the effect of gluten-free diet on mineral and bone metabolism in women with celiac disease and, using strontium test, to assess intestinal calcium absorption. Methods We studied body mass index, biochemical indices, absorption density 18 (mean age 36.8 yr, range 18-68 yr) at diagnosis after 12 months diet. Results: Mean was markedly decreased respect control values (13.84 ± 9.03% vs 22.47 4.21%,p < 0.0001), 11 patients (61%, subgroup A) had low values. In all patients, mean hemoglobin, serum potassium, magnesium, plasma calcium, urinary phosphorus were significantly abnormal diagnosis, whereas only A reduced 25 OH vitamin D, elevated alkaline phosphatase. This differed index (p 0.003) calciuria 0.035) other patients. Strontium correlated calcemia, D. After diet, variables normalized (23.23 5.54%), did not change. Conclusions At frequently malabsorption, as demonstrated by an early renal compensatory mechanism. normalization decrease mid-molecule parathyroid hormone suggested a metabolism, although positive evident that time.