摘要: Nonsurgical treatment of clinically important mitral regurgitation (MR) has evolved tremendously over the past decade. Recent studies percutaneous valve repair procedures have shown that less invasive are safe and can be effective in selected patients. MitraClip been studied most extensively. The is attached to middle scallop leaflets by a transseptal-transvascular approach. device approximates an edge-to-edge technique diminishes MR, improves functional status, left ventricular remodeling. subgroup benefit includes patients with older age, poorer function, MR considered high risk for surgical replacement. Other novel therapies under investigation include indirect direct annuloplasty, remodeling devices.