The Impact of Gut Microbiota on Liver Injury

摘要: Alterations in gut microbiota patients with chronic liver diseases were first noted more than 80 years ago. Increasing translocation of microbial products from the leaky is considered one major contributors to onset and progression disease. With advancement next-generation sequencing technology, detailed information about link between intestinal disease has been intensively studied animals humans. Trillions bacteria colonize are a symbiotic state healthy subjects. The disruption this homeostasis, including certain harmful bacterial overgrowth reduction beneficial bacteria, known as dysbiosis affects health profoundly. Understanding connecting changes composition function well physiology pathology will promote development strategies for prevention drug target identification. In chapter, we discuss how homeostasis disrupted diseases, focusing on alcoholic nonalcoholic disease, review their treatments.