Oxalate Transport in LLC-PK1 Cells: Evidence for Oxalate Transport by Anion Exchange
作者： S. Ebisuno , H. Koul , L. Renzulli , M. Menon , C. Scheid
DOI: 10.1007/978-1-4615-2556-1_9
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摘要: Previous studies of renal oxalate handling have demonstrated that can be transported by a number anion transport systems within the kidney including SO4 2-/oxalate exchanger on basolateral (abluminal) and apical (luminal) membranes1, 2 Cl/oxalate membranes3, 4. These pathway(s) exist for transcellular flux, but technical limitations with membrane vesicles (limited timecourse due to small intravesicular volumes) micropuncture control composition extracellular space) made it difficult predict magnitude or direction this flux under normal pathological conditions. Thus present examined LLC-PK1 cells, epithelial cell line many characteristics proximal tubular cells5 as possible model system assessing handling.
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