Effects of Long-Term Neuroleptic Treatment on Serum Levels of Prolactin, TSH, LH, and Norepinephrine and on α-Adrenergic and Dopaminergic Receptor Sensitivity

作者: Dieter Naber , Franz Müller

DOI: 10.1007/978-1-4684-4529-9_34

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摘要: Neuroendocrine effects of catecholamine receptor-blocking neuroleptic drugs have been investigated in numerous studies (Ackenheil, 1981; Brambilla et al., 1979a; Burt 1977; Carlsson, 1978, Collu Ettigi 1976; Meltzer 1978; Pandey Sachar, 1978); particular, the increase serum prolactin (PRL) after acute treatment is well documented (Gruen Langer Rubin and Hays, 1980, Wode-Helgodt, 1977). There are, however, only a few dealing with neuroendocrine chronic treatment. As both differ distinctly, inferring long-term from short-term inappropriate (Ler-ner Moreover, there are striking differences reactivity tuberoinfundibular, nigrostrial, mesolimbic, mesocortical dopaminergic systems to neuroleptics (Bowers Rozitis, 1974; Julou

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