Biventricular pacing diminishes the need for implantable cardioverter defibrillator therapy

摘要: OBJECTIVES We sought to test the postulate that biventricular pacing diminishes need for appropriate tachycardia therapy. reviewed frequency of therapy in patients, serving as their own controls, who were enrolled Ventak CHF (congestive heart failure) study. BACKGROUND It is well established both acute and chronic contribute tachyarrhythmia recipients an automatic implantable cardioverter defibrillator (ICD). Synchronized (BV) a new promising symptomatic improvement selected patients (low ejection fraction, intraventricular conduction delay). this will diminish METHODS Participants trial received triple-chamber ICD with transvenous right ventricular lead left (LV) placed via thoracotomy. Of 54 trial, 32 could be analyzed, each completing three blinded months programmed BV VDD second randomly assigned three-month period no pacing. RESULTS 13 (41%) at least once six-month monitoring postimplant. Five (16%) had one tachyarrhythmic episode while pacing, whereas 11 (34%) Three (9%) periods, two only. The decrease necessary during was statistically significant (p = 0.035). CONCLUSIONS In standard indications also have CHF, LV dysfunction, delay, less common mechanism unclear but may related hemodynamic CHF. Although does not obviate ICD, it patients.